Induction of Human Anti-Human Antibody Responses (Ab2) after Application of a Humanized Lewis Y Carb

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Purpose: Detailed analysis of a patient with epithelial Lewis Y (LeY) positive cancer who received twice 50 mg of the humanized Lewis Y carbohydrate specific mAb IGN311 and developed a clinically significant human anti-human antibody (HAHA) response (Ab2)
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