近年来,胰腺癌的发病率呈逐年上升趋势,其早期症状不明显,发现时多属晚期,且侵袭性强,恶性程度高,手术切除率低,预后极差,5年生存率仅5%[1],死亡率接近100%,在美国已成为癌症死亡的第四大病因[2]。治疗主要以外科切除为主,但切除率低,只有10%~15%[3]。5-FU、吉西他滨、顺铂等能减缓肿瘤的进展,提高病人的生活质量,但对于胰腺癌 In recent years, the incidence of pancreatic cancer has been increasing year by year, its early symptoms are not obvious, it is mostly late, and it has strong invasiveness, high degree of malignancy, low surgical resection rate and poor prognosis. The 5-year survival rate is only 5%. [1] The mortality rate is close to 100% and has become the fourth leading cause of cancer death in the United States [2]. Treatment is mainly surgical resection, but the resection rate is low, only 10% to 15% [3]. 5-FU, gemcitabine, cisplatin, etc. can slow down the progression of cancer and improve the patient’s quality of life, but for pancreatic cancer