脑胶质瘤是最常见的颅内肿瘤,呈侵袭性生长,临床预后较差。其侵袭过程是一个复杂的多步骤连续过程,涉及到粘附分子、酶类、细胞因子、基因调控等多方面的因素。对其侵袭性的研究将对临床治疗产生积极的影响。本文就脑、胶质瘤侵袭过程及相关因素的研究现状作一综述。 Glioma is the most common intracranial tumor, was invasive growth, clinical prognosis is poor. Its invasion process is a complex multi-step continuous process, involving many factors such as adhesion molecules, enzymes, cytokines, gene regulation and so on. Research on its aggressiveness will have a positive effect on clinical treatment. This article reviews the research progress of brain and glioma invasion and related factors.