5年前,首次报道在芬兰的一次A群脑膜炎球菌病流行期间,对3月龄～5岁儿童应用A群脑膜炎球菌多糖菌苗的现场试验获得成功。在这项研究中,13万名儿童接种A群脑膜炎球菌多糖菌苗;49,000名儿童接种b型流感嗜血杆菌多糖菌苗;32,000名儿童未接种菌苗作为对照。结果第1组在接种后第1年内未发生A群脑膜炎球菌病,后2组 Five years ago, for the first time, a field trial of a group A meningococcal polysaccharide vaccine for children aged 3 months to 5 years was successfully reported during a first outbreak of meningococcal disease in Finland. In this study, 130,000 children were vaccinated against group A meningococcal polysaccharide vaccine, 49,000 children were vaccinated against Haemophilus influenzae type b bacilli, and 32,000 children were unvaccinated as controls. Results Group 1 did not develop meningococcal group A in the first year after inoculation, and the latter two groups