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p2 7KIP1是在 1994年发现的一种细胞周期蛋白依赖性激酶抑制剂[1] 。它的过度表达能引起肿瘤细胞在G1到S期的阻断 ,与多种肿瘤形成有关。我们应用敏感而特异的免疫组化SP法 ,检测胃癌组织及正常胃组织中p2 7KIP1蛋白的表达 ,探讨 p2 7KIP1在胃癌发生、发展中的
p2 7KIP1 is a cyclin-dependent kinase inhibitor found in 1994 [1]. Its overexpression can cause tumor cells in the G1 to S phase of the block, and a variety of tumor formation. We use sensitive and specific immunohistochemical SP method to detect the expression of p2 7KIP1 protein in gastric cancer tissue and normal gastric tissue to explore the p2 7KIP1 in the occurrence and development of gastric cancer