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最近,Walker等建立了唾液孕酮(P_0)放射免疫测定,提供了可靠的正常周期妇女黄体功能指标。本文试图评价唾液P_0测定在估计卵巢功能失调及观察这些患者对诱导排卵疗法反应中的作用。15名志愿者(18～35岁),预先观察6个月,月经规律(27.9±1.6,均值±SD),每天收集唾液标本。多数志愿者在周期第7～23天间断收集血浆标本,至少一个完整周期。在不孕诊所经一系列激素检查,基础体温(BBT)测定、腹腔镜检和子宫内膜活检,选择黄体期异常10例,高催乳素血症(>500IU/l)2例,
Recently, Walker et al. Established a salivary progesterone (P_0) radioimmunoassay that provides reliable luteal function indicators for women with normal cycles. This article attempts to evaluate the role of salivary P_0 in estimating ovarian dysfunction and in observing the response of these patients to induction of ovulation therapy. Fifteen volunteers (18-35 years old), pre-observed for 6 months and menstrual regularity (27.9 ± 1.6, mean ± SD), collected saliva specimens daily. Most volunteers in the cycle of 7 to 23 days intermittent collection of plasma samples, at least one complete cycle. In infertility clinics, 10 cases of abnormal luteal phase, 2 cases of hyperprolactinemia (> 500 IU / l) were selected by a series of hormone tests, basal body temperature (BBT), laparoscopy and endometrial biopsy.