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用日本Ｔｏｐｃｏｎ公司生产的ＳＰ．１０００型角膜内皮显微镜对４６例各类单侧原发性青光眼患者双眼角膜内皮细胞进行照相，健眼作为对照。发现急性闭角型青光眼（急闭青）和慢性闭角型青光眼（慢闭青）患者患眼的角膜内皮细胞密度平均差值分别为９．５９％，１０．６１％，差异均有显著性（Ｐ＜０．０１）；慢性单纯型青光眼（慢单青）患眼与健眼角膜内皮细胞密度平均差值为０．２３％，差异无显著性（Ｐ＞０．０５）；滤过性手术前后角膜内皮细胞密度平均差值为８．２０％，差异有显著性（Ｐ＜０．０１）；虹膜周边切除术前、后角膜内皮细胞密度平均差值０．１９％，差异无显著性（Ｐ＞０．０５）。提示急性持续性高眼压可对角膜内皮细胞有损害。行抗青光眼手术时，术前应尽量了解角膜内皮细胞情况；术中应减少手术器械进入前房的机会，同时尽可能保持前房存在，以减少对角膜内皮细胞的损害
Made with Japan’s Topcon SP. 1000 corneal endothelium microscope in 46 cases of various types of unilateral primary glaucoma patients with corneal endothelial cells, healthy eyes as a control. The average differences in corneal endothelial cell density in patients with acute angle-closure glaucoma (ACI) and chronic angle-closure glaucoma (AMI) were 9.59% and 10.61%, respectively, with significant differences (P <0.01). The difference of average density of corneal endothelial cells in chronic simple glaucoma (slow single cyanine) and healthy cornea was 0.23%, there was no significant difference (P> 0.05) The average difference of corneal endothelial cell density before and after surgery was 8.20%, the difference was significant (P <0.01). The average difference of corneal endothelial cell density before and after iridectomy was 0.19%, with no significant difference (P> 0.05). Prompt high intraocular pressure of acute corneal endothelial cell damage. Line anti-glaucoma surgery, preoperative corneal endothelial cells should try to understand the situation; intraoperative surgical instruments should reduce the chance of entering the anterior chamber, while maintaining the existence of anterior chamber as much as possible to reduce the damage to the corneal endothelial cells