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观察了37例高原健康人和40例高原红细胞增多症(HAPC)患者服用复方天棘胶囊后的血液流变学变化。结果显示:HAPC者及健康人服药后血液流变学指标均有显著改善,全血比粘度,血浆比粘度显著下降(P<0.01),反映红细胞变形能力的红细胞滤过指数(RCIF)、红细胞电泳时间也显著下降(P<0.01)。证实该药能明显降低血液粘稠度,对于改善血循环及微循环,提高组织灌注和抗缺氧能力有较明显的作用。
Observed 37 cases of plateau healthy people and 40 cases of high plateau polycythemia (HAPC) patients after taking the compound Tianke capsule blood rheology changes. The results showed that the hemorheology indexes of HAPC and healthy people were significantly improved after taking the medicine, the specific viscosity of whole blood and the specific viscosity of plasma were significantly decreased (P<0.01), and the red cell filtration index (RCIF) reflecting the deformability of red blood cells was shown. The red blood cell electrophoresis time also decreased significantly (P<0.01). It was confirmed that the drug can significantly reduce the blood viscosity, and has obvious effects on improving the blood circulation and microcirculation, increasing tissue perfusion and anti-hypoxic capacity.