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报告1例头颈部皮肤淋巴上皮瘤样癌(LELCs)。患者女,84岁。左颞部一粉红色丘疹样皮损,表面破溃。皮损组织病理检查示肿瘤细胞呈团巢状分布,癌巢周围见大量淋巴细胞浸润。免疫组化示肿瘤细胞广谱细胞角蛋白(CKp)、上皮膜抗原(EMA)、CK5/6弥漫阳性(+++),细胞核抗原(Ki-67)约40%阳性,白细胞共同抗原(LCA)、CK7、CK20、CD68、HMB-45、S-100蛋白及EB病毒阴性。诊断:头颈部皮肤淋巴上皮瘤样癌。术后随访1年,患者未见复发。
One case of head and neck cutaneous lymphoepithelioma (LELCs) was reported. Female patient, 84 years old. Left temporal pink papule-like lesions, ulceration on the surface. Histopathological examination showed that the tumor cells were neoplasm distribution, see a large number of lymphocytes around the cancer nest infiltration. Immunohistochemistry showed that cytokeratin (CKp), epithelial membrane antigen (EMA), CK5 / 6 diffusely positive (+++), about 40% positive of nuclear antigen (Ki-67), leukocyte common antigen ), CK7, CK20, CD68, HMB-45, S-100 protein and Epstein-Barr virus. Diagnosis: Head and neck skin lymphoid epithelioid carcinoma. Follow-up 1 year after surgery, no recurrence in patients.