Parkinson s disease (PD) is a neurodegenerative disease with the major pathology being the progressive loss of dopaminergic (DA)neurons at the substantial n
Cellular senescence is a complex stress response with two main features: a stable, essentially irreversible arrest of cell proliferation (growth), and a mul
Injury to the central nervous system leads to irreversible neuron loss and the formation of a glial scar.This scar is initially beneficial for restricting s
Reduced levels of neurogenesis and microvasculature, and chronic lowlevel inflammation in the form of astrocyte hypertrophy and activated microglia are amon
The Grand Global Challenge for healthcare systems worldwide is the quandary of how to balance the relative ' costs' of investing in research on 'prevention'