患者女,36岁,干部。三年前因皮肤紫癜月经过多,严重血小板减少,曾诊为原发性血小板减少性紫癜。经用强的松治疗好转,血小板数正常后停药。半年之后患者疲乏无力,多汗,消瘦,食欲不振,脾肿大,白细胞数升高,于81年8月25日入院诊治。当时体温、脉膊,血压均正常,贫血貌,皮肤粘膜无黄染及出血点,全身浅表淋巴结不肿大,胸骨无压痛,肺肝界第五肋间,心前区Ⅱ级缩鸣,肝肋下1cm,脾肋下7cm,质中等硬。血色素7g％,白细胞计数284500,中性分叶核30％,淋巴细胞6％,嗜酸性细胞2％,嗜硷性细胞5％,原粒3％,早幼粒7％,中幼粒10％,晚幼粒17％,杆状核20％,血小板32.9万。骨體检查:增生极度活跃,以中晚幼粒及成熟粒细胞为主,原始粒十早幼粒占7％。红系统受抑制。巨核系统增生明显活跃,全 Female patient, 36 years old, cadre. Three years ago due to skin purpura, menorrhagia, severe thrombocytopenia, had diagnosed with primary thrombocytopenic purpura. After treatment with prednisone, platelets normal after withdrawal. Six months after the patient fatigue, sweating, weight loss, loss of appetite, splenomegaly, increased white blood cell count, admitted to hospital on August 25, 81 treatment. At that time, body temperature, pulse, blood pressure were normal, anemia appearance, skin and mucosa without yellow dye and bleeding point, systemic superficial lymph nodes does not enlarge, no tenderness in the sternum, the fifth intercostal space between lung and liver, precordial level Ⅱ Ming, liver 1cm under the ribs, spleen ribs 7cm, medium hard. Hemoglobin 7g%, white blood cell count 284500, neutral lobular 30%, lymphocytes 6%, eosinophils 2%, basophils 5%, 3% of the original particles, promyelocytic 7%, 10% , Late juvenile 17%, 20% of the rod nucleus, platelet 329,000. Bone examination: Hyperplasia is extremely active, mainly in the late young and mature granulocytes, primordial granulosa promyelocytic accounted for 7%. Red system is suppressed. Megakaryocyte hyperplasia was significantly active