目前对ＨＢＶ相关性肾炎的研究指出，ＨＢＶ相关性肾炎的发病机制是ＨＢＶ抗原—抗体复合物沉积在肾小球时导致肾脏免疫损伤及ＨＢＶ直接感染肾脏组织致病。为了解慢性乙肝患者是否早期出现肾脏损害，预测转归，观察血β２－ＭＧ及三项尿微量蛋白变化有重要临床意义。１　材料 At present, the study on HBV-associated nephritis indicates that the pathogenesis of HBV-associated nephritis is renal immune injury caused by the deposition of HBV antigen-antibody complex in the glomerulus and pathogenicity of the kidney directly infected by HBV. To understand whether chronic hepatitis B patients with early renal damage, prediction of prognosis, blood β2-MG and three trace protein changes have important clinical significance. 1 material