在治疗初期,左旋多巴对帕金森病的症状有很高的缓解效果,但最终出现了两个问题。第一是治疗数年后开始出现运动神经的退废,如运动障碍和运动神经的波动(逐渐减退和开关现象),迫使医生小心地调整左旋多巴的给药量和给药时间。这些运动神经综合征与那些直接作用于多巴胺主动肌的药物,如单胺 In the early stages of treatment, levodopa symptoms of Parkinson’s disease have a very high relief, but eventually two problems. The first is the treatment of a few years after the start of motor nerve withdrawal, such as dyskinesia and motor nerve fluctuations (gradual decline and switch phenomenon), forcing doctors to carefully adjust the dose and administration of levodopa time. These motor neurological syndromes are associated with those drugs that act directly on dopamine agonists, such as monoamines