1726例患者急性期用全量的甲氰咪胍治疗获得成功后,改用每晚400mg 维持治疗达3年,并定期作内窥镜检查。如果病情复发,给予全量,愈复后再改为每晚400mg 剂量。生命表分析表明有症状的溃疡复发,在治疗的第一年占病人总数的18%,第二年占8%,第三年占6%。无症状的溃疡复发第一年占7%,第二三年皆为3%。 After successful treatment of 1726 patients with the full dose of cimetidine in the acute phase, they switched to 400 mg of maintenance treatment for up to 3 years per night and were routinely underwent endoscopy. If the disease recurrence, given the full amount, the more complex and then changed to 400mg dose per night. The life table analysis showed that symptomatic ulcer recurrence accounted for 18% of patients in the first year of treatment, 8% in the second year and 6% in the third year. The first year of asymptomatic ulcer recurrence accounted for 7%, the second three years are 3%.