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目的观察慢性阻塞性肺疾病病人在常用药物治疗基础上加用体外反博对患者肺功能影响。方法收集武汉钢铁(集团)公司第二职工医院2014年2月至2015年6月确诊并收治的慢性阻塞性肺疾病患者82例,随机分成治疗组(n=42)和对照组(n=40),对照组应用常规药物,治疗组在常规药物基础上应用体外反搏,治疗前后应用血气分析、肺功能检测及6分钟步行法评定肺功能及运动耐量。结果治疗组总有效率达88.09%,显著高于对照组的62.50%,差异有统计学意义(P<0.05)。治疗组和对照组患者的肺功能及血气分析指标pH、PaO_2、第1秒用力呼气容积(FEVl)、用力肺活量(FVC)、FEV1/FVC分别较治疗前显著升高,PaCO_2较治疗前显著降低,差异均有统计学意义(P<0.05);且治疗组治疗后的FEV1、FVC、6 min步行距离(6MWD)显著高于对照组治疗后,PaCO_2显著低于对照组治疗后,差异均有统计学意义(P<0.05)。结论在药物治疗基础上应用体外反搏治疗可提高患者肺功能及生活质量,且安全,有效,值得临床推广应用。
Objective To observe the effect of anti-Bo in vitro on pulmonary function in patients with chronic obstructive pulmonary disease (COPD) based on commonly used medical therapy. Methods 82 patients with chronic obstructive pulmonary disease diagnosed and admitted from February 2014 to June 2015 in the Second Workers’ Hospital of Wuhan Iron and Steel (Group) Company were collected and randomly divided into treatment group (n = 42) and control group (n = 40) ). The control group was treated with conventional drugs. The treatment group was treated with EECP on the basis of routine drugs. Blood gas analysis, pulmonary function test and 6-minute walk method were used to evaluate the lung function and exercise tolerance before and after treatment. Results The total effective rate of the treatment group was 88.09%, which was significantly higher than that of the control group (62.50%), the difference was statistically significant (P <0.05). The pulmonary function and blood gas analysis indexes of the patients in the treatment group and the control group were significantly higher than those before the treatment (P <0.05), PaCO 2, FEV 1, FVC and FEV 1 / FVC, (P <0.05). The FEV1, FVC and 6MWD walking distance in the treatment group after treatment were significantly higher than those in the control group after treatment PaCO_2 was significantly lower than the control group after treatment, the difference was There was statistical significance (P <0.05). Conclusion The application of external counterpulsation in the treatment based on drug therapy can improve lung function and quality of life of patients, and is safe and effective, which is worthy of clinical application.