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目的了解我国居民白酒中氨基甲酸乙酯的暴露状况并对其健康风险进行评估。方法利用2002年中国居民营养与健康状况调查18岁及以上人群白酒消费量数据和2010—2011年全国25省白酒中氨基甲酸乙酯调查数据,采用@Risk软件对人群白酒氨基甲酸乙酯健康风险进行概率风险评估。结果 2010—2011年白酒中氨基甲酸乙酯的平均含量为0.072 mg/kg。18岁以上人群白酒氨基甲酸乙酯每日平均暴露量为8.09 ng/kg BW,暴露限值为37 083,个体暴露限值超过引起公共卫生关注度的概率为0.052。白酒饮酒者氨基甲酸乙酯每日平均暴露量为159.99 ng/kg BW,暴露限值为1 875,饮酒者个体暴露限值超过引起公共卫生关注度的概率为0.455。结论18岁及以上人群白酒氨基甲酸乙酯暴露的健康风险较低,但白酒饮酒者存在较高健康风险。
Objective To understand the status of urethane exposure in Chinese liquor and evaluate its health risk. Methods Using the data of Chinese population health and alcohol consumption in 2002 to investigate the liquor consumption data of 18 years old and above and the survey data of ethyl carbamate in 25 provinces of China from 2010 to 2011, the health risk of ethyl alcohol Probabilistic risk assessment. Results The average content of ethyl carbamate in white wine from 2010 to 2011 was 0.072 mg / kg. The mean daily exposure of ethyl carbamate to alcohol in adults over 18 years of age was 8.09 ng / kg BW, with a limit of exposure of 37 083 and a probability of 0.052 for individual exposure limits exceeding public health concerns. The mean daily exposure of urethane to liquor drinkers was 159.99 ng / kg BW, with a limit of exposure of 1,875. The individual alcohol exposure limit exceeded the public health concern of 0.455. Conclusions There is a lower health risk of exposure to ethyl carbamate in people aged 18 and over, but there is a higher health risk among those drinking alcohol.