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端粒酶是一种具有特殊性质的逆转录酶 ,能以自身的RNA为模板合成约 10 kb的端粒重复序列。端粒酶在大多数肿瘤细胞、干细胞、淋巴细胞中有表达。我们以前的研究显示 :正常人外周血单个核细胞 ( PBMC)可表达端粒酶活性 [1 ]。人端粒酶主要由 3部分组成 ,即 ,端粒酶 RNA( h TR) ,
Telomerase is a special type of reverse transcriptase that synthesizes a telomeric repeat of about 10 kb using its own RNA as a template. Telomerase is expressed in most tumor cells, stem cells and lymphocytes. Our previous study showed that normal human peripheral blood mononuclear cells (PBMCs) express telomerase activity [1]. Human telomerase consists mainly of three components, namely, telomerase RNA (hTR),