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1981年5月11日至15日在澳大利亚的西澳州首府Perth召开了第四届《人和动物微量元素代谢国际讨论会》(简称TEMA-4)。会议由澳大利亚科学院、澳大利亚营养学会和西澳州政府主办。参加者有20个国家240名代表。大会共收到178篇论文,多数论文是关于硒、锌和铜的研究。研究的内容比较广泛,但多数是研究元素缺乏的生化表现或代谢方面的问题,元素间的相互关系或与其他疾病的关系。 Prohaska教授报告了铜、硒、锌缺乏时脑中酶的变化,指出妊娠或授乳时,缺铜使子代脑中的有些酶活力降低,其中包括三种含铜的酶:细胞色素氧化酶、多巴胺-β-羟化酶和超氧化物歧化酶。此外铜缺
The Fourth International Symposium on Trace Metabolism in Human and Animal Metabolism (TEMA-4) was held May 11-15, 1981 in Perth, Western Australia, Australia. The conference is hosted by the Australian Academy of Sciences, the Australian Nutrition Society and the Western Australian State Government. There are 240 delegates in 20 countries. The conference received a total of 178 papers, the majority of papers on selenium, zinc and copper research. The research contents are quite extensive, but most of them are the study of the biochemical performance or metabolic problems of the lack of elements, the interrelationship among elements or the relationship with other diseases. Prof. Prohaska reported changes in brain enzymes in the absence of copper, selenium and zinc, noting that copper deficiency during pregnancy or lactation resulted in decreased activity of some of the enzymes in the progeny brain, including three copper-containing enzymes: cytochrome oxidase, Dopamine-β-hydroxylase and superoxide dismutase. In addition copper deficiency