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作者研究了61例因较小的动脉硬化性血栓形成而住院治疗的卒中患者(平均年龄66±10岁,男42例,女19例)。在急性期(病后7天内)给予10％甘油400～600ml/d或低分子右旋糖酐500mg/d。大多数患者有一个腔隙性梗塞灶(<1.5cm)。在1个月的研究期内没有任何患者使用非类固醇类抗炎药。30例患者接受噻氯匹啶(200mg/d),另31例患者接受阿司匹林(81mg/d)。使用噻氯匹啶200mg/d的剂量是按照日本人的标准。测定了发病后使用抗血小板药物前和2～4周后血浆纤维蛋白原浓度及血小板聚集情况。对全血和富含血小板的血浆
The authors studied 61 stroke patients hospitalized for smaller arterial thrombosis (mean age 66 ± 10 years, 42 males and 19 females). In the acute phase (within 7 days after illness) given 10% glycerol 400 ~ 600ml / d or low molecular weight dextran 500mg / d. Most patients have a lacunar infarct (<1.5 cm). None of the patients used non-steroidal anti-inflammatory drugs during the 1-month study period. Thirty patients received ticlopidine (200 mg / d) and the other 31 received aspirin (81 mg / d). Dosage of ticlopidine 200mg / d is in accordance with Japanese standards. Determination of the incidence of antiplatelet drugs before and after 2 to 4 weeks of plasma fibrinogen concentration and platelet aggregation. Whole blood and platelet-rich plasma