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目的:研究舰船上0.1Hz极低频交变磁场和恒定磁场全身暴露的生物效应及其作用阈值。方法:实验动物全身间断暴露于25~100mT交变或恒定磁场7或14天,或连续暴露于3mT交变磁场5或10天;然后分别测定其对微血管、神经肽、骨髓及免疫功能的影响。结果:当场强在75和100mT时,实验兔球结膜毛细血管和微静脉显著扩张,而在25和50mT时也有扩张趋势。场强在75和100mT时,大鼠下丘脑和垂体及血浆中β-内啡肽(β-Ep)和精氨酸加压素(AVP)含量显著升高,在25和50mT时作用不明显,而3mT交变磁场使含量下降。场强在75mT时,对实验兔和大鼠骨髓细胞增生活力有非常显著的促进作用。结论:磁场具有扩张微血管、改善微循环的作用,且随着场强的增大,作用逐渐加强。低强度磁场抑制神经肽的合成与分泌,高强度促进合成与分泌。强场在75mT时,对骨髓细胞增生活力有非常显著的促进作用。交变和恒定磁场的场强和暴露时间相同时,对机体的影响基本一致
OBJECTIVE: To study the biological effect and its action threshold of 0.1Hz very low frequency alternating magnetic field and constant magnetic field whole body exposure on ships. Methods: The experimental animals were intermittently exposed to alternating or constant magnetic fields of 25-100 mT for 7 or 14 days, or continuously exposed to 3 mT alternating magnetic fields for 5 or 10 days. The effects on microvessels, neuropeptides, bone marrow and immune function . Results: The conjunctival capillaries and venules were significantly expanded at 75 and 100 mT on the spot, but also expanded at 25 and 50 mT. At 75 and 100 mT, the content of β-endorphin (β-Ep) and arginine vasopressin (AVP) in the hypothalamus, pituitary and plasma were significantly increased at 25 and 50 mT , While 3mT alternating magnetic field to reduce the content. Field strength at 75mT, experimental rabbit and rat bone marrow cell proliferation has a very significant role in promoting. Conclusion: The magnetic field has the function of dilating capillaries and improving microcirculation. With the increase of field strength, the effect of magnetic field gradually strengthens. Low-intensity magnetic field inhibition of neuropeptide synthesis and secretion, high-intensity synthesis and secretion. Strong field at 75mT, the proliferation of bone marrow cell proliferation has a very significant role. Alternating and constant field strength and exposure time the same time, the impact on the body are basically the same