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[Objective]To research the chemical components in FRUCTUS GARDENIAE. [Methods]Silica column chromatography over silica gel,RP-18 reverse phase silica gel and Sephadex LH-20,as well as recrystallization were adopted. Structures of compounds were identified by1H-NMR,13C-NMR,ESI-MS,EI-MS and comparison with the data of literatures. [Results]A total of seven chemical compounds were isolated and purified from the ethanol extracts of FRUCTUS GARDENIAE,which were geniposide( 1),6α-hydroxygeniposide( 2),genipingentiobioside( 3),adian-5-en-3α-ol( 4),( 23Ζ)-cycloart-23-en-3β,25-diol( 5),7α-hydroxy sitosterol( 6) and 5,8-epidioxystigmasta-6,22-dien-3-ol( 7). [Conclusions] Compounds 4,5,6 and 7 were isolated from FRUCTUS GARDENIAE for the first time.
[Objective] To research the chemical components in FRUCTUS GARDENIAE. [Methods] Silica column chromatography over silica gel, RP-18 reverse phase silica gel and Sephadex LH-20, as well as recrystallization were. Structures of compounds were identified by 1H- NMR , 13C-NMR, ESI-MS, EI-MS and comparison with the data of literatures. [Results] A total of seven chemical compounds were isolated and purified from the ethanol extracts of FRUCTUS GARDENIAE, which were geniposide (1) hydroxygeniposide (2), genipingentiobioside (3), adian-5-en-3α-ol (4), (23Ζ) -cycloart- 23-en-3β, 25- diol 5,8-epidioxystigmasta-6,22-dien-3-ol (7). [Conclusions] Compounds 4,5,6 and 7 were isolated from FRUCTUS GARDENIAE for the first time.