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双八面体蒙脱石干混悬剂 ( Dioctahedral Sm ectite for Suspension,DSS) ( 8,4 g/ kg,po) ,对大黄液所致小鼠腹泻有显著止泻作用 ( P<0 .0 1) ;可显著延缓脾虚小鼠的黑粪排出时间 ( P<0 .0 1) ;可显著抑制由新斯的明产生的小鼠小肠推进机能亢进作用 ( P<0 .0 1) ;可显著抑制脾虚小鼠小肠推进功能 ( P<0 .0 1,P<0 .0 5) ;对正常小鼠小肠推进功能无明显影响。DSS( 4 ,2 g/ kg)对连续 po番泻叶液一个月的慢性腹泻大鼠有显著止泻作用 ( P<0 .0 1,P<0 .0 5)
Dioctahedral Sm ectite for Suspension (DSS) (8, 4 g / kg, po) had a significant anti-diarrhea effect on mice induced by rhubarb (P <0.01) ); Can significantly delay the excretion of black manure of spleen deficiency mice (P <0.01); can significantly inhibit the mice intestinal propulsive hyperactivity caused by neostigmine (P <0.01); can significantly Inhibit small intestine promote function of mice with spleen deficiency (P <0.01, P <0.05), and had no significant effect on small intestine propulsion function in normal mice. DSS (4, 2 g / kg) had a significant anti-diarrheal effect on chronic diarrhea rats with continuous po senna (P <0.01, P <0.05)