论文部分内容阅读
目的 探讨下丘脑 垂体 靶腺轴变化与急性脑血管病 (CVD)的发生、发展的相关性及临床意义。方法 采用放射免疫法检测血浆中甲状腺激素 (T3 、T4) ,促甲状腺激素 (TSH) ,肾上腺皮质激素 (Cor) ,促肾上腺皮质激素 (ACTH) ,性腺激素睾酮 (T) ,雌二醇 (E2 )、促性腺激素 (FSH)的含量。结果 CVD急性期T4、TSH、Cor、ACTH、T、E2 、FSH的含量明显增高 ,T3 的含量下降 (P <0 .0 1)。随着病情的好转各项指标有所恢复。结论 CVD患者下丘脑 垂体 靶腺轴均有改变 ,是可逆的。及时测定观察有关激素的含量变化对诊断疾病 ,预测病情及预后 ,指导治疗有着实际的临床意义。
Objective To investigate the relationship between the changes of hypothalamus pituitary gland axis and the occurrence and development of acute cerebrovascular disease (CVD) and its clinical significance. Methods The plasma levels of thyroid hormone (T3, T4), thyroid stimulating hormone (TSH), adrenocorticotropic hormone (COR), adrenocorticotropic hormone (ACTH), gonadotropin testosterone (T), estradiol ), Gonadotropin (FSH) content. Results The contents of T4, TSH, Cor, ACTH, T, E2 and FSH in acute phase of CVD were significantly increased while the content of T3 was decreased (P <0.01). As the condition improved, the indicators recovered. Conclusion The hypophyseal pituitary gland in the patients with CVD has a change in the target gland axis and is reversible. Timely measurement observed changes in the content of hormones on the diagnosis of disease, prognosis and prognosis, guiding treatment has practical significance.