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我们用亚硒酸钠及维生素E治疗病毒性肝炎65例,取用益肝炎、护肝片等治疗病毒性肝炎43例做为对照组,除检测肝功能生化指标外,还检测了谷胱甘肽过氧化物酶(GSH-Px);过氧化氢酶(CAT);过氧化物歧化酶(SOD)及过氧化脂质(LPO)。结果显示该药可提高患者血中GSH-Px活性,降低LPO浓度,P<0.01均有极显著差异性,说明该药在病毒性肝炎治疗中抗氧化损伤及清除自由基有明显疗效,而在短期内对CAT及SOD无影响。
We use sodium selenite and vitamin E in the treatment of viral hepatitis in 65 cases, take the use of hepatitis, liver tablets and other treatment of viral hepatitis in 43 cases as a control group, in addition to testing biochemical indicators of liver function, but also test the glutathione Peptide peroxidase (GSH-Px); catalase (CAT); superoxide dismutase (SOD) and lipid peroxidation (LPO). The results show that the drug can increase GSH-Px activity in patients with blood, reduce LPO concentrations, P <0.01 were significantly different, indicating that the drug in the treatment of viral hepatitis antioxidant and free radical scavenging significant effect, In the short term no effect on CAT and SOD.