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目的探讨抗人类免疫缺陷病毒(HIV)阳性患者合并感染乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、梅毒螺旋体(TC)的重叠感染的致病机制及特点。方法对20份HIV-1抗体阳性血清,采用酶联免疫吸附试验(ELISA)法、微粒子酶免疫技术(MELA)、甲苯胺红不加热血清凝集试验(TRUST)等方法对其感染状况进行分析。结果 20例HIV感染者中合并HBV、HCV、TP总感染率为75%,合并感染HBV者11例(55%),合并感染HCV者11例(55%),合并感染HCV、TP者2例(10%)。结论对HIV感染者常规进行HBV、HCV的相关检查并积极采取相关的预防治疗措施。
Objective To investigate the pathogenesis and characteristics of over-infection of hepatitis B virus (HBV), hepatitis C virus (HCV) and Treponema pallidum (TC) in patients with anti-HIV infection. Methods Twenty HIV-1 positive sera were tested for their infection by ELISA, MELA, TRUST and so on. Results The total infection rates of HBV, HCV and TP in 20 HIV-infected patients were 75%, 11 cases (55%) were complicated with HBV infection, 11 cases (55%) were complicated with HCV infection and 2 cases were infected with HCV and TP (10%). Conclusions HIV and HCV are routinely tested for HBV and HCV, and relevant preventive measures are taken actively.