运动神经元病(motor neurol disease,MND)是一组病因不明的慢性进行性变性疾病,传统认为本病选择性侵犯脊髓前角细胞、脑干运动神经元、皮质锥体细胞和锥体束,表现为肌无力、肌萎缩和锥体束征的不同组合,而忽略了对MND运动区域以外脑组织功能的研究。近年来,国外学者对神经心理 Motor neurol disease (MND) is a group of chronic progressive degenerative diseases with unknown etiology. Traditionally, it is thought that this disease selectively attacks spinal cord anterior horn cells, brainstem motor neurons, cortical pyramidal cells and pyramidal tract, Manifested as different combinations of myasthenia, amyotrophy, and pyramidal tract signs, ignoring the study of brain function outside of the MND locomotion area. In recent years, foreign scholars on neuropsychology