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目的分析OGTT不同取血次数对妊娠糖尿病(GDM)诊断的影响。方法对1506例50g葡萄糖负荷试验(GCT)阳性的孕妇进行3hOGTT,观察各时间点组合的10种诊断方法的灵敏度、漏诊率、总符合率、阴性预测值等指标,并与标准诊断方法相比进行一致性检验。结果 1-2-3h法诊断GDM的Kappa值为0.936(P<0.01)。结论对50gGCT阳性的孕妇行OGTT时,FPG对GDM的诊断影响最小,如需减少取血次数,可考虑取消之。
Objective To analyze the influence of different blood sampling times of OGTT on the diagnosis of gestational diabetes mellitus (GDM). Methods 1506 pregnant women with 50g glucose load test (GCT) were treated with 3-hour OGTT. The sensitivity, misdiagnosis rate, total coincidence rate and negative predictive value of 10 diagnostic methods at different time points were observed. Compared with the standard diagnostic methods Conduct a consistency check. Results The Kappa value of diagnosis of GDM by 1-2-3h method was 0.936 (P <0.01). Conclusion When OGTT is administered to a 50gGCT positive pregnant woman, the effect of FPG on the diagnosis of GDM is minimal. If it is necessary to reduce the number of blood transfusions, it may be considered canceled.