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C—反应蛋白(C—reactive protein简称CRP)是在某些疾病的急性期出现于患者血液中的一种特殊蛋白质,它能与肺炎球菌菌体的两种多糖体起沉淀反应,故称为丙种反应蛋白或C反应蛋白。理论依据1930年Tillett等用各种肺炎球菌的提取物对肺炎患者作了血清学检查,发现一种非特异的菌体多糖成分可与急性肺炎患者的血清发生沉淀。该多糖成分称C——组分。随后Avery等发现C反应物是一种蛋白质,它与C—组分反应时要有钙离子参加,并命名为CRP。通过实残,证实CRP是机体多数感染和非感染炎症时,细胞和组织损伤的一种非特异性反应。
C-reactive protein (C-reactive protein referred to as CRP) is a special protein that appears in the blood of patients during the acute phase of certain diseases and can react with two polysaccharides of pneumococcal bacteria to precipitate, so it is called Acreactive protein or C-reactive protein. Theoretical basis Tillett and other 1930 with a variety of pneumococcal extracts of patients with pneumonia were serologically tested and found that a non-specific polysaccharide components of bacterial pneumonia patients with serum sedimentation. The polysaccharide component called C-- component. Then Avery et al. Found that the C-reactant was a protein that had calcium ions when it reacted with the C-component and was named CRP. Through the real residue, CRP is confirmed to be a nonspecific reaction of cell and tissue damage in most infected and noninfected tissues.