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本文合成了Cu(L-Dopa)_2及(L-Dopa)-Cu-ATP两种络合物。初步的结构分析证实在本文所给条件下,L-Dopa以氨基及羧基与Cu~(++)配位。用昆明种小鼠所做的抗震颤实验结果表明,Cu-(L-Dopa)_2及(L-Dopa)-Cu-ATP的抗震颤作用分别比L-Dopa提高54％与140％,而三者的LD_(50)相近。
In this paper, Cu (L-Dopa) _2 and (L-Dopa) -Cu-ATP complexes were synthesized. Preliminary structural analysis confirmed that under the conditions given in this paper, L-Dopa with amino and carboxyl and Cu ~ (++) coordination. Anti-tremor experiments using Kunming mice showed that the anti-tremor effects of Cu- (L-Dopa) 2 and (L-Dopa) -Cu-ATP increased 54% and 140% LD_ (50) are similar.