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本文报告应用光镜和电镜对20例精素静脉曲张不育症患者的睾丸和附睾组织进行了病理改变和超微结构的观察。生精细胞脱落、间质小血管病变和对侧睾丸病理损害是精素静脉曲张不育症睾丸的三种主要病理变化,其中间质小血管病变更具有特征性。电镜发现精原细胞存在着明显的病理变化,因此精索静脉曲张不育症患者精子生成障碍涉及到精原细胞的增殖,精母细胞的成熟分裂及细胞变态三个过程。病检表明附睾有一定损害,具有重要病理生理意义,认为是精索静脉曲张导致不育的重要因素。
This article reports the application of light microscopy and electron microscopy of 20 cases of varicocele patients with testicular and epididymal tissue pathological changes and ultrastructural observation. Spermatogenic cell shedding, interstitial small blood vessel lesions and contralateral testicular pathological lesions are the three major pathological changes of the testes of the varicocele infertility, of which interstitial small vessel lesions are more characteristic. Electron microscopy found spermatogonia there is a clear pathological changes, so varicocele infertility in patients with spermatogenesis involves spermatogonial proliferation, spermatocyte maturation and cell metamorphosis three processes. Disease examination showed that there is a certain damage to the epididymis, has an important pathophysiological significance, that is an important factor leading to varicocele infertility.