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维库溴胺(Vecuronium)是一种临床上常用的中短时效非去极化肌松药,其具有对循环功能影响小,不释放组织胺,肌松效果佳等优点。本文报告该药静脉持续输注在小儿麻醉中应用体会。资料和方法 45例择期手术病例随机分为三组,每组15例,其中Ⅰ、Ⅱ组为先心病。实施低温体外循环下纠治术;平均年龄5～6岁,平均体重16～22kg;Ⅲ组为腹部及颅脑手术,平均年龄6岁,平均体重14～25kg。三组病人术前肝、肾功能均无明显异常。麻醉方法三组术前用药均为安定0.2mg·kg~(-1),阿托品0.02mg·kg~(-1)(青紫型先心病病人以吗啡0.1mg·kg~(-1)替代安定)术前30分肌注。麻醉诱导
Vecuronium is a clinically used short and medium-acting non-depolarizing muscle relaxant, which has the advantages of little effect on circulatory function, no release of histamine and good muscle relaxation effect. This article reports the drug intravenous infusion in pediatric anesthesia experience. Materials and Methods 45 cases of elective surgery were randomly divided into three groups, 15 cases in each group, of which Ⅰ, Ⅱ group was congenital heart disease. The implementation of low temperature cardiopulmonary bypass surgery; the average age of 5 to 6 years old, the average body weight 16 ~ 22kg; Ⅲ group of abdominal and cranial surgery, mean age 6 years, average body weight 14 ~ 25kg. Three groups of patients with preoperative liver and kidney function were no significant abnormalities. Anesthesia The three groups were given 0.2mg · kg -1 of diazepam and 0.02mg · kg -1 of atropine respectively (diazepam with 0.1 mg · kg -1 of diazepam instead of diazepam) 30 minutes before surgery intramuscularly. Anesthesia induction