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过去10年,曾报道伴局限性皮质变性的选择性进行神经心理学缺陷,包括后部皮质局限性萎缩引起的进行性失用、失认或视觉性定向障碍及与额叶内侧皮质代谢减退有关的步态失用,大多数进行局限性皮质变性病例涉及与言语有关的障碍,尤其是健忘性失语.本文报道一例不同于既往的进行性和选择性言语障碍.患者,65岁,右利,工程师.58岁出现说话困难,言语渐进性不流畅,且内容贫乏;诉阅读和理解困难;书写缓慢,伴拚写和语法错误.但仍能进行复杂工作,无记忆、行为、情感及判断力障碍.以后患者的言语表达能力进行性损害,60岁就诊时
In the past 10 years, selective neuropsychological deficits with localized cortical degeneration have been reported, including progressive loss of a posterior cortical atrophy, degenerative or visual disorientation, and an impaired metabolism of the medial frontal cortex , Most of the cases of localized cortical degeneration involve speech-related disorders, especially amnestic aphasia.This article reports a case of progressive and selective speech disorders other than previous.Patients, 65 years old, Engineer. Difficulty speaking at 58, poorly graduated speech, and poor content; Poor reading and comprehension skills; Slow writing, spelling and grammatical errors. Still complex work, memorylessness, behavior, emotion, and judgment Obstacles. After the patient’s speech ability of progressive damage, 60-year-old treatment