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1例9月龄男婴因发热、咳嗽静脉滴注头孢曲松钠后体温降至正常,但出现面色苍白,哭闹不安,食欲减退。2 d后停用头孢曲松钠,改为肌内注射青霉素,患儿再次出现低热。2 d后血常规检查:血红蛋白67 g/L,红细胞2.95×1012/L,白细胞22.16×109/L,中性粒细胞0.30,淋巴细胞0.60,单核细胞0.07,异性淋巴细胞0.03。给予头孢曲松钠0.9 g入10%葡萄糖注射液100 ml静脉滴注,氨溴索15 mg入莫菲滴管滴注。输液约70 ml时,患儿出现面色苍白、烦躁哭闹,排棕红色尿,呼吸喘促。实验室检查:血红蛋白27 g/L,红细胞1.75×1012/L,网织红细胞0.045;直接抗人球蛋白试验C3 1∶4;尿潜血(+++),红细胞2～8个/HP。立即停用头孢曲松钠,输注红细胞及甲泼尼龙冲击治疗。第6天血常规示血红蛋白111 g/L,红细胞3.83×1012/L,患儿病情好转。
One case of 9-month-old boy was fever, cough intravenous infusion of ceftriaxone after the temperature dropped to normal, but appeared pale, crying uneasy, loss of appetite. After 2 days, ceftriaxone was discontinued and intramuscular injection of penicillin was given. The child again developed fever. 2 d after the blood test: hemoglobin 67 g / L, red blood cells 2.95 × 1012 / L, white blood cells 22.16 × 109 / L, 0.30 neutrophils, lymphocytes 0.60, mononuclear cells 0.07, 0.03 of lymphocytes. Give ceftriaxone 0.9 g into 10% glucose injection 100 ml intravenous infusion of ambroxol 15 mg into the Murphy dropper. Infusion of about 70 ml, the children appear pale, irritable crying, row of red-brown urine, breathing wheezing. Laboratory tests: hemoglobin 27 g / L, erythrocytes 1.75 × 1012 / L, reticulocyte 0.045; direct anti-human globulin test C3 1: 4, urine occult blood (+++), red blood cells 2 to 8 / HP. Ceftriaxone sodium was stopped immediately, red blood cells and methylprednisolone infusion were administered. The sixth day blood showed hemoglobin 111 g / L, red blood cells 3.83 × 1012 / L, children with improved condition.