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目的 观察肝癌患者介入性热化疗栓塞前后红细胞的免疫性改变及其临床意义。方法 采用“郭峰法”检测 30例原发性肝癌患者外周血中红细胞 C3bRR和红细胞 ICR的含量 ,及其在肝动脉热化疗栓塞后的变化 ,并与对照组进行比较。结果 肝癌组治疗前红细胞 C3bRR明显减少 ,红细胞 ICR明显增加 ,与对照组比较有非常显著差异 (P <0 .0 1)。治疗后红细胞 C3bRR升高、红细胞 ICR下降 ,治疗前后比较亦有非常显著差异 (P <0 .0 1)。结论 检测肝癌患者红细胞的免疫性有助于肝癌的诊断 ,对其疗效和预后的评估更有重要意义
Objective To observe the changes of erythrocyte immunity before and after interventional chemoembolization in patients with hepatocellular carcinoma and its clinical significance. Methods The levels of erythrocyte C3bRR and erythrocyte ICR in peripheral blood of 30 patients with primary hepatic cancer were detected by “GuoFeng method”, and their changes after embolization with hepatic artery thermotherapy were compared with those of the control group. Results Before treatment, the C3bRR of erythrocytes and the ICR of erythrocytes were significantly increased in HCC group compared with the control group (P <0.01). After treatment, erythrocyte C3bRR increased, erythrocyte ICR decreased, before and after treatment there are also very significant differences (P <0.01). Conclusion Detecting the immunity of HCC patients with red blood cells is helpful to the diagnosis of HCC, and it is more important to evaluate its curative effect and prognosis