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目的 总结中国医学科学院肿瘤医院 30余年下咽癌治疗的经验。方法 初程以根治性治疗为目的收治的下咽癌病例 2 6 2例 ,术前放射治疗加手术 14 6例 (5 5 .7% ) ,单纯放射治疗 80例(30 .5 % ) ,手术加术后放射治疗 17例 (6 .5 % ) ,单纯手术治疗 19例 (7.3% )。全组分为 6 0～ 70年代、80年代和 90年代 3个治疗时期 ,分析各时期病例的特点、治疗方法、放射治疗技术和预后。结果 随着治疗方法和技术的改进 ,5年总生存率和无瘤生存率分别由 6 0～ 70年代的 14 .3%和 2 3.8%提高到 90年代的 6 2 .2 %和 5 3.7%。结论 疾病分期、原发灶部位、治疗方法和照射技术影响预后。
Objective To summarize the experience of treatment of hypopharyngeal cancer in the Cancer Hospital of Chinese Academy of Medical Sciences for more than 30 years. Methods A total of 226 cases of hypopharyngeal carcinoma were treated with radical radiotherapy for the first time. There were 146 cases (57.5%) undergoing radiotherapy and surgery before operation, 80 cases (30.5%) undergoing radiotherapy alone, Seventeen patients (6.5%) received radiotherapy and 19 patients (7.3%) received surgery alone. The whole group consisted of three treatment periods from the 1960s to the 1970s, the 1980s and the 1990s. The characteristics of the cases, treatment methods, radiotherapy techniques and prognosis were analyzed. Results With the improvement of the treatment methods and techniques, the 5-year overall survival and tumor-free survival rate increased from 14.3% and 23.8% in the 1960s to the 1970s to 62.2% and 53.7% in the 1990s, respectively . Conclusion The stage of the disease, the location of the primary tumor, the treatment method and the irradiation technique affect the prognosis.