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目的：探讨不同的洗胃方法对治疗百草枯中毒患者的疗效。方法选取2010年7月~2015年7月在山东省菏泽市立医院治疗被确诊的急性百草枯中毒患者108例，随机分为分为3组。A组37例，常规温清水加碳酸氢钠洗胃；B组35例，在A组的基础上，洗胃后，温清水加白陶土（白）或活性炭（黑）口服；C组36例，是在B组的基础上，洗胃液中加白陶土和洗胃液加活性炭交替洗胃。比较各组患者肝肾功能、中毒性心肌炎、多功能脏器衰竭（Multiple Organ Disfunction Syndrome,MODS）的发生率和病死率等变化。3组间均数比较采用方差或秩和检验，两两比较采用LSD法。多个率比较采用非校正χ2检验。结果 C组患者肝肾功能、中毒性心肌炎、MODS的发生率、病死率和存活时间等指标明显优于B组和A组（P<0.01），而B组患者的各项指标又优于A组（P<0.05）。结论碳酸氢钠稀释液加白陶土与碳酸氢钠稀释液加活性炭交替洗胃和口服，可以减轻百草枯对患者各个器官的损害，降低患者病死率。“,”Objective To explore the efficacy of different methods to treat patients with paraquat poisoning. Methods A total of 108 cases of patients who were admitted into our hospital from July 2010 to July 2015 due to acute paraquat poisoning were enrolled into the current study. They were randomized into three groups. Group A was subjected to gastric lavage using warm water and sodium bicarbonate (n=37). Group B was orally taken warm water plus white clay (white) or activated carbon (black) (n=35), in addition to routine therapy in Group A. Group C was subjected to gastric lavage using white clay and activated carbon alternatively, based on Group B’s therapy (n=36). Then, these groups were compared for hepatic and renal function, toxic myocarditis, multifunctional organ failure (MODS) incidence and mortality. Results Group C presented the hepatic and renal function, incidence of toxic myocarditis and multifunctional organ failure (MODS), mortality and survival rate which were superior to Groups A and B (P<0.01). Group B presented the hepatic and renal function, incidence of toxic myocarditis and multifunctional organ failure (MODS), mortality and survival rate which were superior to Group A (P<0.05). Conclusion Sodium bicarbonate diluents containing white clay and activated carbon can be adopted alternatively for gastric lavage, which relieve paraquat-induced injury in patients’organs and reduce patient mortality.