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目的了解厦门市湖里区2001—2012年急性迟缓性麻痹发病情况和分布特点,为巩固无脊灰成果和制定决策提供依据。方法通过分析脊髓灰质炎疫苗的预防接种、AFP主动和被动监测情况,调查脊髓灰质炎病毒疫苗相关病例(VAPP)。结果口服脊灰减毒活疫苗在消灭脊灰和维持无脊灰阶段起着决定性的作用,免疫低下婴幼儿发生VAPP病例的危险性更大。结论建议将2和3月龄脊髓灰质炎灭活疫苗纳入第一类疫苗管理。
Objective To understand the incidence and distribution characteristics of acute retardation paralysis in Huli District of Xiamen City from 2001 to 2012, and to provide the basis for consolidating the results of polio-free development and making decisions. Methods Poliovirus vaccine-related cases (VAPP) were investigated by analyzing the immunization of poliomyelitis vaccines and the active and passive AFP surveillance. Results Oral live attenuated oral poliomyelitis vaccine plays a decisive role in the eradication of polio and in the maintenance of non-polio stage. Immunocompromised infants and young children are at higher risk of VAPP. Conclusions It is recommended that 2 and 3 months old poliomyelitis inactivated vaccines be included in the first category of vaccine management.