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目的结合临床实践及文献报道资料,对1,2—二氯乙烷发病条件、诊断要点、临床特点及预防与治疗等进行总结,以期提高对该病的认识和诊治水平,更好地指导今后的防治工作。方法临床实践结合文献报道资料进行分析总结。结果中毒后在常规处理基础上,严格控制加重脑水肿的诱因、积极防治脑水肿、加强脑功能恢复治疗则预后良好;早期采取积极预防措施效果满意。结论治疗原则以防治“脑水肿”为重点,同时要保护肝、肾、心脏等重要脏器的功能,强调“密切观察、早期发现、及时处理、防止反复”的治疗原则;“早发现、找代替、禁加班、要通风、勤监测”的预防措施,证明对预防职业性二氯乙烷急性中毒,特别是预防以中毒性脑病为主要表现的职业性二氯乙烷急性中毒是有效的。
OBJECTIVE To summarize the incidence, diagnosis, clinical features, prevention and treatment of 1,2-dichloroethane in order to improve the understanding and diagnosis and treatment of 1,2-dichloroethane and to better guide the future Prevention and control work. Methods Clinical practice combined with literature reports were analyzed and summarized. Results After poisoning, on the basis of routine treatment, the causes of aggravating cerebral edema were strictly controlled, and the prevention and treatment of cerebral edema was proactively controlled. The prognosis was good with the improvement of brain function recovery treatment. The early preventive measures were satisfactory. Conclusion The treatment principle focuses on the prevention and treatment of cerebral edema and at the same time protects the functions of important organs such as liver, kidney and heart, emphasizing the treatment principle of “close observation, early detection, timely treatment and prevention of repeated” Preventive measures to prevent occupational dichloroethane from being acutely poisoned, especially for the prevention of occupational dichloroethane, a major manifestation of toxic encephalopathy, have been shown to be “precautionary measures such as early detection, replacement, ban on overtime, ventilation and diligent monitoring” Acute poisoning is effective.