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精制破伤风抗毒素(精破抗)系破伤风免疫马血浆经胃酶消化后用盐析法提制的抗毒素球蛋白制剂。用于治疗及预防破伤风,注射前必须作过敏试验,但临床中精破抗迟发反应引起过敏性休克较少见,现报告如下。患者,男,18岁,学生。因铁钉刺伤左侧脚底疼痛伴出血,急来我院就诊,清创包扎后给予精破抗1500u 预防注射。皮试20min 后,皮丘直径约1cm,周围轻度发红,但不高于皮肤,阳性可疑,遂进行脱敏注射。当第4次肌注后。约3min,患者感到局部发痒、麻木,颜面发强,四肢、躯干出现皮疹并伴头晕、恶心、胸闷、气短、
Purified tetanus antitoxin (fine broken anti-anti) Department of tetanus immune horse plasma digested with gastric enzyme anti-toxin globulin preparation. For the treatment and prevention of tetanus, allergy test must be done before injection, but in clinical anti-delayed reaction caused by anaphylactic shock is rare, are as follows. Patient, male, 18 years old, student. Because of nail stabbing left foot pain with bleeding, urgent to our hospital for treatment, debridement after bandage to give anti-1500u injection. Skin test 20min, Picchia diameter of about 1cm, around the mild redness, but not higher than the skin, positive suspicious, then desensitized injection. After the 4th intramuscular injection. About 3min, the patient felt itchy, numb, facial hair strong, limbs, torso rash and accompanied by dizziness, nausea, chest tightness, shortness of breath,