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目的探讨儿童阻塞性睡眠呼吸暂停综合征(OSAS)对耳蜗功能的影响。方法将2002年6月至2003年8月广州市儿童医院收治的26例(52耳)OSAS患儿的畸变产物耳声发射(DPOAE)的结果与28例(56耳)正常儿童DPOAE结果进行比较。结果26例OSAS患儿多导睡眠图(PSG)示最低血氧饱和度(57.91±18.61),呼吸紊乱指数(29.10±23.31),与正常儿童相比差异均有显著性意义。OSAS患儿F1～F4频率段DPOAE反应幅值与正常组比较,差异无显著性意义(P>0.05);F4～F11频率段的DPOAE反应幅值及F1～F11频率段DPOAE检出率均较正常儿童低,差异有显著性意义(P<0.05)。结论OSAS能导致患儿耳蜗功能受损,对OSAS患儿应常规做耳声发射检查,做到早诊断、早治疗。
Objective To investigate the effect of obstructive sleep apnea syndrome (OSAS) on cochlear function in children. Methods The results of distortion product otoacoustic emissions (DPOAE) in 26 children (52 ears) with OSAS admitted to Children’s Hospital of Guangzhou from June 2002 to August 2003 were compared with those of 28 children (56 ears) normal children . Results The polysomnography (PSG) of 26 OSAS children showed the lowest oxygen saturation (57.91 ± 18.61) and the index of respiratory disorder (29.10 ± 23.31), which were significantly different from those of normal children. There was no significant difference in DPOAE amplitude between F1 ~ F4 frequency group and normal group (P> 0.05). The DPOAE response amplitude in F4 ~ F11 and DPOAE in F1 ~ F11 Normal children with low, the difference was significant (P <0.05). Conclusion OSAS can lead to impaired cochlear function in children, and OSAS should be performed routinely for otoacoustic emission testing. Early diagnosis and early treatment should be done.