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患者男,11岁。因全身奇痒皮疹一天,于1978年12月23日入院。于前二天注射流行性脑脊髓膜炎吸附菌苗(上海生物制品研究所出厂,批号7813—4)0.5毫升,4～5小时后,躯体发痒,发现腹背部散在皮疹,次日奇痒加重,皮疹遍及全身,曾服扑尔敏、苯海拉明一天,奇痒更甚,皮疹增多,以往无类似发作史。体检:体温37.2℃,脉搏76次/分,呼吸22次/分,血压100/70毫米汞柱。心肺(-),肝脾未及,全身皮疹密集遍布,有的融合成片状,高出皮肤,色红,压之能退色,多处有搔痕。白细胞10800,中性78%,淋巴22%。尿常规正常,大便蛔虫卵(+)。诊断为流脑吸附菌苗所致过敏反应。
Patient male, 11 years old. Due to the whole body itchy rashes one day, in December 23, 1978 admission. In the first two days before the injection of epidemic meningococcal meningitis vaccine (Shanghai Institute of Biological Products factory, lot number 7813-4) 0.5 ml, 4 to 5 hours later, the body itching, found in the abdomen scattered rash, itchy aggravated the next day , Rash throughout the body, had served chlorpheniramine, diphenhydramine one day, even more itchy itchy, rash increased in the past no similar episodes of history. Physical examination: body temperature 37.2 ℃, pulse 76 beats / min, breathing 22 beats / min, blood pressure 100/70 mm Hg. Cardiopulmonary (-), liver and spleen not yet, the whole body rashes intensively distributed, and some integration into a sheet, higher than the skin, color red, the pressure can fade, many scratches. White blood cells 10800, 78% neutral, lymph 22%. Normal urine, stool roundworm eggs (+). Diagnosed as meningitis adsorbed vaccine-induced allergic reactions.