论文部分内容阅读
目的了解重症急性胰腺炎患者用血液净化手段联合治疗对病情的影响作用以及临床效果。方法将在2014年12月-2016年12月期间本院收治确诊的重症急性胰腺炎患者180例随机分成对照组与观察组,每组90例,对照组患者用常规对症综合治疗,观察组患者除综合治疗外联合血液滤过与血液灌流等血液净化手段治疗。比较不同治疗手段后患者病情、体征等各项检测情况。结果治疗前后各项生命体征包括T、HR、RR以及MAP,炎症因子水平包括TNF-α、IL-6、hs-CRP以及PCT等均有所改善,观察组各项指标改善程度明显优于对照组,组间数据差异统计学处理显示P<0.05。结论对重症急性胰腺炎患者除常规综合对症治疗外联合血液净化手段能够对患者体征有更好的改善效果,缩短症状消失以及康复时间,值得临床推广。
Objective To understand the effect of combined therapy of blood purification and its clinical effect on patients with severe acute pancreatitis. Methods 180 patients with severe acute pancreatitis diagnosed in our hospital from December 2014 to December 2016 were randomly divided into control group and observation group with 90 cases in each group.The patients in the control group were treated with conventional symptomatic treatment and the patients in the observation group In addition to the combined treatment of blood filtration and hemoperfusion and other blood purification treatment. After comparing different treatment methods, the patient’s condition, signs and other detection conditions. Results Before and after treatment, all the vital signs including T, HR, RR and MAP, the levels of inflammatory cytokines including TNF-α, IL-6, hs-CRP and PCT were all improved. The indexes of observation group were better than those of control Data between groups and between groups showed statistically significant difference (P <0.05). Conclusion In addition to conventional combined symptomatic treatment of patients with severe acute pancreatitis in combination with blood purification can improve the patient’s signs and symptoms, shortening the disappearance of symptoms and recovery time, is worthy of clinical promotion.