移植体动脉硬化是大器官移植慢性排斥反应三大病理学特征之一[1] 。目前 ,在移植体动脉硬化过程中细胞增生ＤＮＡ复制与ＰＣＮＡ的表达研究已有报道[2 ] 。但是在移植体动脉硬化中Ｃ ｍｙｃ表达以及Ｃ ｍｙｃ与ＰＣＮＡ表达、细胞凋亡两者之间有何关系 ,尚缺乏了解。我们在建立 Graft arteriosclerosis is one of the three major pathological features of chronic allograft rejection [1]. At present, in the process of graft atherosclerosis cell proliferation DNA replication and PCNA expression has been reported [2]. However, the relationship between C-myc expression and C-myc and PCNA expression and apoptosis in graft atherosclerosis is still poorly understood. We are building