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对符合〈CCMD—2〉诊断标准的64例精神分裂症患者进行治疗前及治疗后4周未做BEAM和EEG观察比较,其氯氮平治疗量控制在200—300mg/天,结果EEG异常率为73.43％,BEAM异常率为82.81％。BEAM异常形式为a频谱功能广泛增高,而以额颞部和顶中失部多见,此与精神分裂症患者额颞部功能低下病理有关。EEG异常者中轻度占18.75％,中度占32.81％,重度占21.87％。所以脑电地形图和脑电图在临床上是观察药疗和副作用的很重要的。
Before and after treatment of 64 patients with schizophrenia who meet the criteria of CCMD-2, the therapeutic effect of clozapine was 200-300mg / day without BEAM and EEG observation. Results The abnormal rate of EEG Was 73.43%, abnormal rate of BEAM was 82.81%. BEAM abnormal form of a spectrum of functions increased widely, but to the frontotemporal and the top of the loss of more common, with schizophrenia in frontotemporal hypoplasia pathology. EEG abnormality accounted for 18.75% of mild, moderate accounted for 32.81%, severe accounted for 21.87%. Therefore, EEG and EEG in clinical observation of drug treatment and side effects is very important.