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作者报道10例震颤性谵妄病人对大剂量苯二氮(艹卓)耐药,静注低剂量地塞米松,易逆转病情。其中1例男性,28岁,在肝、脾裂伤缝合术和血胸引流术后出现震颤,安定治疗无效,进展为震颤性谵妄,在14h内逐渐增加利眠宁剂量,每次达100mg,每2h静注一次无效,开始静注地塞米松,每次3mg,12h1次,震颤性谵妄缓解,生命体征正常,停止激素治疗,恢复顺利。另1例男性,50岁,震颤性谵妄伴有脂肪栓塞,对大剂量利眠宁耐药,每天静注地塞米松4mg好转。作者认为,如用大剂量的地塞米松,疗效会更迅速显著。其机理在于地塞米松无矿物皮质素的
The authors report 10 patients with tremor delirium of high-dose benzodiazepine (Qiu Zhuo) resistance, intravenous low-dose dexamethasone, easy to reverse the disease. One case of male, 28 years old, trembled after hepatic and splenic laceration and hemothoracic drainage, diazepam treatment was ineffective and progression to tremor delirium, gradually increase the dose of Sheleuoning within 14h, up to 100mg each time, Every 2h intravenous once invalid, began dexamethasone intravenous injection, each 3mg, 12h1 times, delirium tremor delirium, vital signs normal, stop hormone therapy, recovery smoothly. The other 1 male, 50 years old, tremor-induced delirium with fat embolism, high-dose Limonin resistant, daily intravenous dexamethasone 4mg improved. The authors believe that if large doses of dexamethasone, the effect will be more rapid and significant. The mechanism is dexamethasone without mineral cortisol