新生儿低氧血症的病因很多 ,而新生儿肺动脉高压是其中的重要原因之一。长期以来 ,临床上一直缺乏能特异性扩张肺血管、降低肺动脉压而又对体循环血压无影响的药物。直到 2 0世纪 80年代初期 ,一氧化氮 (ｎｉｔｒｉｃｏｘｉｄｅ ,ＮＯ)的发现才令人们重新看到了希望。大量的动 Neonatal hypoxemia, many causes, and neonatal pulmonary hypertension is one of the important reasons. For a long time, there has been a lack of clinical drugs that can specifically expand pulmonary blood vessels, reduce pulmonary arterial pressure and have no effect on systemic blood pressure. It was not until the early 1980s that the discovery of nitric oxide (NO) led to renewed hope. A lot of action