论文部分内容阅读
1970年以后催乳激素(prolactin,以下简称为prl)才和生长激素区分开来,确定为一种独立的激素。电子显微镜观察,它是由脑垂体前叶后侧面的含分泌颗粒最粗的prl细胞所分泌。prl是一种蛋白激素,分子量为2600,半衰期为15~20分钟。由于垂体含量很微,不允许在体内直接进行研究,直至近年来发展了敏感的特异性强的放射免疫方法,进一步阐明了prl分泌的调节机制以及高催乳激素血症(hyperprolactinemia)和多种病理状态的关系。
After 1970 prolactin (prolactin, hereinafter referred to as prl) and growth hormone were separated, identified as an independent hormone. Electron microscopy, which is secreted by the coarser prl cells containing the secreted granules behind the anterior pituitary gland. prl is a protein hormone, molecular weight of 2600, half-life of 15 to 20 minutes. Due to the small amount of pituitary, direct studies in the body are not allowed until recent years, the development of a sensitive and specific radioimmunoassay method to further clarify the regulatory mechanism of prl secretion and hyperprolactinemia (hyperprolactinemia) and a variety of pathologies The relationship between the state.