烟酸是一种降血脂药物,它在体内转化为烟酰胺后,发挥药理作用,后者是辅酶Ⅰ和辅酶Ⅱ的组成部分,参与体内脂质代谢,组织呼吸的氧化过程和糖原分解的过程。烟酸还可降低辅酶A的利用;通过抑制密度蛋白的合成而影响胆固醇的合成,大剂量尚可降低血清胆固醇及甘油三酯的浓度,且有 Niacin is a hypolipidemic drug that acts pharmacologically after it is converted to niacinamide in the body, which is a component of coenzyme I and coenzyme II and is involved in the metabolism of lipids, the oxidation of tissue respiration, and glycogenolysis process. Niacin can also reduce the use of coenzyme A; by inhibiting the synthesis of density proteins and affect the synthesis of cholesterol, high doses can still lower serum cholesterol and triglyceride concentrations, and there