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目的观察美托洛尔联合硝酸甘油治疗冠心病心绞痛的临床疗效。方法将204例冠心病心绞痛患者随机分为观察组和对照组各102例。2组均给予强心、利尿、吸氧等基础治疗,在此基础上,观察组给予美托洛尔联合硝酸甘油进行治疗,对照组仅给予硝酸甘油进行治疗。比较2组的临床疗效和不良反应发生情况。结果观察组的总有效率为90.20%高于对照组的64.71%,差异有统计学意义(P<0.05),治疗期间2组患者均未发生严重不良反应。结论美托洛尔联合硝酸甘油治疗冠心病心绞痛具有较好的临床疗效,且不良反应少,值得临床推广使用。
Objective To observe the clinical efficacy of metoprolol combined with nitroglycerin in the treatment of angina pectoris. Methods 204 patients with coronary heart disease angina pectoris were randomly divided into observation group and control group of 102 cases. The patients in the two groups were given basic treatment such as cardiac, diuretic and oxygen inhalation. On the basis of this, the observation group was treated with metoprolol combined with nitroglycerin, and the control group only with nitroglycerin. The clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate in the observation group was 90.20%, which was significantly higher than that in the control group (64.71%, P <0.05). No serious adverse reactions occurred in the two groups during the treatment. Conclusion Metoprolol combined with nitroglycerin in the treatment of angina pectoris has better clinical curative effect, and less adverse reactions, it is worthy of clinical promotion and use.