白介素８（ＩＬ－８）是由多种细胞合成与分泌的一种细胞因子，它对中性粒细胞具有强大的趋化和激活作用，诱导其形态改变及细胞内贮存酶颗粒的释放，ＩＬ－８亦可趋化嗜碱粒细胞及Ｔ－淋巴细胞，目前其分子及基因结构都已清楚。成人呼吸窘迫综合征（ＡＲＤＳ）时，血清及支气管肺泡灌洗液中ＩＬ－８均明显升高，它参与了肺内白细胞的募集、活化与肺泡－毛细血管的损伤，在ＡＲＤＳ的发病中有重要作用。 Interleukin-8 (IL-8) is a cytokine synthesized and secreted by many kinds of cells. It has strong chemotactic and activation effects on neutrophils, induces its morphological changes and release of intracellular storage enzyme particles, IL -8 also chemotaxis basophils and T-lymphocytes, the molecular and genetic structure of its current have been clear. In the case of adult respiratory distress syndrome (ARDS), IL-8 in serum and bronchoalveolar lavage fluid are significantly increased, it is involved in the recruitment of leukocytes in the lung, activation and alveolar-capillary damage in the pathogenesis of ARDS Important role.